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Tim-4 plays an important role in the proliferation of T helper type 2 (Th2) cells
cancer progression and metastasis
resulting in questionable data interpretation
The new variant of IL-2 called H9T
Fluorescein-5-thiosemicarbazide anti-CD16 Tim-4 plays an important roleHydrazide derivative of fluorescein. An amine containing cell impermeant fluorescent probe that can be reversibly coupled to aldehydes and ketones on diverse molecules. This forms a Schiff base which can be further reduced to generate stable amine derivatives by treatment with reducing agents such as sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNH3). Carboxylic acids of proteins and other water soluble biopolymers can also be coupled to
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