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The chemical glutathione is essential to good health
Moving toward a systems-level understanding, empowered by interactomics, CRISPR technologies, AI-driven modeling and precision biomarker science, will profoundly transform how we interpret disease biology and develop therapeutics
3 Its side effects have been classified into two groups: those that cause symptoms only, such as nausea, headaches, lethargy, mucositis, and alopecia, and those that could lead to fatal conditions, such as cytopenia, interstitial lung pathology, or MTX-induced pneumonitis, and hepatic conditions, such as fibrosis and cirrhosis
miR-150-5p [117] targets the downregulation of SLC38A1 to inhibit ferroptosis, whereas some miRNAs may promote ferroptosis by targeting SLC7A11
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