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Cancer Res 54: 43134320

TGF- is a cytokine exerting immunosuppressive functions in the TME (112) and it was shown to modulate the expression of CD16 and thus the NK cell cytotoxic potential (113)

Phase Initial 4 weeks Daily Dose 300 mcg Volume 0.18 mL Units (U-100) 18 units Phase Maintenance (weeks 5-12) Daily Dose 500 mcg Volume 0.30 mL Units (U-100) 30 units Phase Optional extension Daily Dose 300-500 mcg Volume 0.18-0.30 mL Units (U-100) 18-30 units This summarizes the published research-context dose range (commonly cited 300-500 mcg/day)

Quoting a generic number without knowing your protocol would be misleading