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In addition, the photoreceptor cells in diabetic mice also showed enhanced levels of iron, ROS, and MDA and reduced GSH concentration with downregulation of GPX4 and SLC7A11, and upregulation of ACSL4, FTH1 and NCOA4, which suggested that ferroptosis is also involved in the pathogenesis of photoreceptor degeneration in the development of the early stages of DR ( 2.7 Other retinal vascular diseases Ferroptosis is also involved in the pathogenesis of other retinal vascular diseases, such as air pollution associated retinal vascular diseases (Vahatupa et al., 2023)

Angelone F, Ciliberti FK, Tobia GP, Jnsson H, Ponsiglione AM, Gislason MK, et al

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0.9% Sodium Chloride Injection IP or