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Patients with acquired GHD may face several confounding factors, including varied etiologies of GHD, pituitary surgery, irradiation, anticonvulsant use, and deficiencies of other pituitary hormones coupled with inadequate replacement therapies (130, 131)

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The timeframe for observing results also plays a role short-term effects might call for a single, higher dose, while long-term studies may benefit from smaller, repeated doses

These and other agents work together to increase oxidative stress in our bodies, creating highly reactive molecules called free radicals that can cause severe damage to our cells