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Retention times for non-natural metabolites, including 5FU, were determined by single compound reference sample analyses, and both molecular weight and retention times were used for analysis in larger LCMS experiments

Also, peptides related to BMPs or those related to cells types or conditions distant to bone healing or bone cells were excluded from the selection process as these were out of the scope of the manuscript

common reactions include transient pain, erythema, or pruritus at the administration site, along with mild diarrhea, headache, or nausea in a minority of recipients

However, these outcomes were specific to the U.S