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doi: 10.1038/ncomms10690 11 SharmaSLeeDLiBQuinlanMTakahashiFMaheswaranSet al

The hexanoic acid modification increases lipophilicity, allowing the molecule to cross lipid membranes more readily than unmodified peptides

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The acute stage of traumatic SCI includes immediate bleeding, accumulation of ROS, and lipid peroxidation, 687 suggesting that the ferroptosis pathway may play an important role in the secondary injury of SCI