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Global loss of desnutrin/ATGL gene function in mice resulted in increased weight gain and a shift in favor of carbohydrate over fat as a primary fuel source during fasting, indicating that in vivo desnutrin/ATGL likely also functions in adipose tissue lipolysis (43)

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A 2025 case-control study from Vietnam found what researchers described as a U-shaped relationship between B12 intake and cancer risk, with both lower and higher intakes associated with increased risk

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